DSPE-PEG-Azide, DSPE-PEG-N3
作者:DSPE-PEG-Azide, DSPE-PEG-N3 发布时间:2022-08-01 09:05:19
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DSPE-PEG-Azide,
DSPE-PEG-N3
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[azido(polyethylene
glycol)]
Synonym: Azide PEG DSPE,N3-PEG-DSPE.
Product
Structure:
Product
Specifications:
l Catalog
Numbers:PS2-DEAZ-1K,2K,3K,5K,10K.
l Appearance: White
to off-white solid.
l Solubility: >10
mg/mL in hot water, chloroform, DCM, Methanol.
l Stability: 1 Years at-20°C, Desiccate.
l CAS
Number: 1938081-40-3.
l Molecular
Weight(PEG):1K,2K,3.4K,5K,10K.
l Purity: 95%.
Description:
1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine
(DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate
which has both hydrophilicity and hydrophobility. Pegylated phospholipids are
excellent liposome formation materials that can be used for drug delivery, gene
transfection and vaccine delivery as well. ruixibio DSPE-PEG-N3 products can be used to prepare pegylated liposome
using Click Chemistry. Azide reacts readily with alkyne or cycloocytne in
aqueous solution with or without copper catalyst. Pegylation of phospholipids
significantly improves the blood circulation time and stability for
encapsulated drugs.
Cu-free click
chemistry with readily synthesized biarylazacyclooctynones. The reaction of
azides with strained alkynes, such as cyclooctynes, readily forms a triazole
product without the need for a toxic catalyst.
Refer also to
DSPE-PEG-DBCO ruixibio Number PS2-AZDE
Handling
and Use:
DSPE
PEG Azide should always be kept in low temperature in dry condition. Prepare fresh
solution right before use.Avoid frequent thaw and freezing. For more
information about using this product, .
Related
Products:
DSPE-PEG-NH2,
DSPE-PEG-COOH
DSPE-PEG-NHS
,DSPE-PEG-FA
DSPE-PEG-SH,DSPE-PEG-MAL
References:
l Hood ED,
Greineder CF, Shuvaeva T, Walsh L, Villa CH, Muzykantov VR. Vascular targeting
of radiolabeled liposomes with bio-orthogonally conjugated ligands: single
chain fragments provide higher specificity than antibodies.
This
product is for research use only and is not intended for use in humans or for
diagnostic use.