DSPE-PEG-NHS,DSPE-PEG-SS
作者:DSPE-PEG-NHS,DSPE-PEG-SS 发布时间:2022-08-01 09:05:19
次浏览
DSPE-PEG-NHS,DSPE-PEG-SS
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[Succinimidyl
Succinate ester(polyethylene glycol)]
Synonym: 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine
PEG NHS, NHS PEG DSPE, DSPE PEG Succinimidyl Succinate ester, DSPE Polyethylene
glycol NHS.
Product
Structure:
Product
Specifications:
l Catalog
Numbers:PS2-HDE-1K,2K,3K,5K,10K.
l Appearance: White
to off-white solid.
l Solubility: 10
mg/mL in hot water, chloroform, DCM, DMSO.
l Stability: 1 Years at-20°C, Desiccate.
l CAS
Number: -
l Molecular
Weight(PEG):1K,2K,3.4K,5K,10K.
l Reactive
group: NHS.
l Reactive
to: Primary amine (-NH2).
l Purity: 95%.
Description:
DSPE-PEG-NHS is one of ruixibio
reactive phospholipid PEG conjugates that can react with primary amine groups.
DSPE(1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon
phospholipid that is highly hydrophobic. PEG backbone, on the other hand,
offers good hydrophilicity and water solubility. Succinimidyl ester (NHS) on
the PEG terminal reacts with primary amine groups efficiently at pH 8~10. DSPE-PEG-NHS can be easily incorporated
into liposome and other nanoparticles. DSPE-PEG-NHS is one of most commonly used reactive phospholipids to conjugate antibodies,
peptides or other ligands to the surface of liposome and other lipid PEG
nanoparticles. Pegylated phospholipids have longer blood circulation time and
higher stability for encapsulated molecules.
Handling
and Use:
DSPE
PEG NHS should always be kept in low temperature in dry condition. Prepare fresh
solution right before use.Avoid frequent thaw and freezing. For more
information about using this product, .
Related
Products:
DSPE-PEG-NH2,
DSPE-PEG-COOH
DSPE-PEG-N3
,DSPE-PEG-FA
DSPE-PEG-SH,DSPE-PEG-MAL
References:
l Biomimetic
virus-like and charge reversible nanoparticles to sequentially overcome mucus
and epithelial barriers for oral insulin delivery------ Acs
applied materials&interfaces(IF=8.097)
l The
combination of endolysosomal escape and basolateral stimulation to overcome the
difficulties of “easy uptake hard transcytosis” of ligand-modified
nanoparticles in oral drug delivery------ Nanoscale(IF=7.233)
l Colorimetric
in situ assay of membrane-bound enzyme based on lipid bilayer inhibition of ion
transport------ Theranostics(IF=8.537)
This
product is for research use only and is not intended for use in humans or for
diagnostic use.