Name:Galanthamine
Synonyms:Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine
CAS Number:357-70-0
Formula:C17H21NO3
M.w.:287.35
DMSO (mg/mL)Max Solubility:100
DMSO (mM)Max Solubility:348.01
Form:free base
SMILES:COC1=C2OC3CC(O)C=CC34CCN(C)CC(=C24)C=C1
ALogP:1.442
Target:AChR
Pathway:Neuronal Signaling
Information:Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.
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