生物活性：Undecane-d24 is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Undecane-d24 相关抗体:
TNF alpha Antibody
TNF Receptor 2 Antibody
CD40 Antibody
CD40L Antibody
DR5 Antibody
TNFAIP3 Antibody (YA2231)
TRADD Antibody (YA2276)
DcR2 Antibody (YA2588)
TNFRSF10B Antibody (YA660)
4-1BB Ligand Antibody (YA1329)
GITR Antibody (YA1333)
BAFFR Antibody (YA1356)
BCMA Antibody (YA1501)
4-1BB Antibody (YA1506)
TNFSF12 Antibody (YA1507)
BAFF Antibody (YA1510)
LIGHT Antibody (YA1512)
GITR-L Antibody (YA1515)
TNFAIP8 Antibody (YA1600)
4 1BBL Antibody (YA2316)
TNFRSF19 Antibody (YA2865)
Optineurin Antibody (YA3127)
Lymphotoxin alpha Antibody (YA3334)
分子量：180.46
Formula：C11D24
CAS 号：164858-54-2
非标记 CAS：1120-21-4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]
[2]. Choi D, Kang W, Park T. Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes. Molecules. 2020;25(7):1554. Published 2020 Mar 28.
 [Content Brief]