生物活性：Saquinavir-d9 (Ro 31-8959-d9) is the deuterium labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Saquinavir-d9 相关抗体:
Annexin VI Antibody
ERK1/2 Antibody
IL-1 beta Antibody
E-Cadherin Antibody (YA470)
IRF3 Antibody
Fatty Acid Synthase Antibody (YA766)
iNOS Antibody
DYKDDDDK Tag (FLAG) Antibody
GAPDH Antibody
GFP Antibody
p53 Antibody (YA250)
RUNX2 Antibody
Ferritin Heavy Chain Antibody
JNK Antibody
Toll-Like Receptor 4 Antibody
COX2 Antibody
Ctip2 Antibody
Cyclin D1 Antibody (YA485)
Cytochrome C Antibody
c-Myc Antibody
Cyclin E1 Antibody
p38 Antibody
Phospho-p38 (Thr180/Tyr182) Antibody
AIF Antibody (YA636)
ALIX Antibody
ASK1 Antibody (YA609)
Calbindin Antibody
Calreticulin Antibody
Catalase Antibody (YA552)
Catalase Antibody (YA811)
分子量：679.90
Formula：C38H41D9N6O5
CAS 号：1356355-11-7
非标记 CAS：127779-20-8
中文名称：沙奎那韦 d9
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (539 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Pettoello-Mantovani M, et al. Saquinavir-mediated inhibition of human immunodeficiency virus (HIV) infection in SCID mice implanted with human fetal thymus and liver tissue: an in vivo model for evaluating the effect of drug therapy on HIV infection in lymphoid tissues. Antimicrob Agents Chemother. 1997 Sep;41(9):1880-7.
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