瑞禧生物货号：Ruixi-B595825
化学名称：BLI 489 Hydrate
同义名称：(5R,6Z)-6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt Hydrate;
CAS号：623564-40-9
Alternate CAS #
635322-76-8-free acid
分子式：C₁₃H₁₀N₃NaO₄S • xH ₂O
Appearance:Yellow Solid
Melting Point:>200°C (dec.)
分子量：327.29
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
产品类别：Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria.
参考文献：Maiti, S., et al.: Curr. Med. Chem., 5, 441 (1998), Barnaud, G., et al.: Antimicrob. Agents Chemother., 48, 1040 (2004), Szabo, D., et al.: J. Clin. Microbiol., 43, 5058 (2005),
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