瑞禧生物货号：Ruixi-B118790
化学名称：BAY 11-7082
同义名称：(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile; (E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile; (E)-3-(p-Tolylsulfonyl)-acrylonitrile; BAY 11-7821; BAY 117821
CAS号：19542-67-7
分子式：C₁₀H₉NO₂S
Appearance:Off-White Solid
Melting Point:129-131°C
分子量：207.25
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
产品类别：Standards; Enzyme Activators and Inhibitors;
产品应用：BAY 11-7082 is a nuclear factor-κB (NF-κB) inhibitor and a potential anti-inflammatory agent. It selectively and irreversibly inhibits NF-κB activation by blocking TNF-a-induced phosphorylation of Iκba without affecting constitutive Iκba phosphorylation. Potent IKK inhibitor
参考文献：Pierce, J.W., et al.: J. Biol. Chem., 272, 21096 (1997); Keller, S.A., et al.: Blood, 96, 2537 (2000); Remacle-Bonnet, M.M., et al.: Cancer Res., 60, 2007 (2000); Thévenod, F., et al.: J. Biol. Chem., 275, 1887 (2000); Petegnief, V., et al.: Neuroscience, 104, 223 (2001); Kauppinen, T.M., et al.: J. Immunol., 174, 2288 (2005)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Delta is committed to providing cost-effective products that facilitate drug delivery with our customers.