Folic acid-PEG-acid,FA-PEG-COOH
作者:Folic acid-PEG-acid,FA-PEG-COOH 发布时间:2022-07-27 14:58:02
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商品型号:R-CMFA-1K,2K,3.4K,5K,10K
英文简称:Carboxylic (polyethylene glycol) folic acid
分子量:1K,2K,3.4K,5K,10K
规格:100mg,500mg
Folicacid-PEG-acid,FA-PEG-COOH
Carboxylic (polyethylene glycol) folic acid
Synonym: Folic acidPEG COOH, Folate PEG COOH, Carboxylic PEG Folate
ProductStructure:
ProductSpecifications:
CatalogNumbers:PS2-CMFA-1K,2K,3.4K,5K,10K.
Appearance: Orange/yellowto brownish solid.
Solubility:5mg/mL in hot water, DMSO.
Stability: 1 Years at-20°C, Desiccate.Protect from light.
CASNumber:-
MolecularWeight(PEG): 1K,2K,3.4K,5K,10K.
Reactivegroup: Acid (-COOH).
Description:
FA-PEG-COOH is one of reactive folate PEG derivatives that have a folic acid on one terminusof PEG chain and a carboxylic (-COOH) group on the other. Folic acid is alsoknown as vitamin M, vitamin B9 or pteroyl-L-glutamic acid. Folic acid is an essentialbioactive molecule for numerous biological functions. It participates in thesynthesis, repairing and methylation of DNA as well as to act as a cofactor in manybiological reactions. Carboxylic acid functionalized folic acid PEG allows theattachment of folic acid to other molecules and materials quickly andefficiently through reaction between COOH and other groups, such as amine,hydryoxyl, etc. PEG linker between COOH and folate offers with higher watersolubility, less steric hindrance and better reactivity. Molecules or materialsconjugated with PEG folic acid are useful for targeted drug delivery, cellularimaging and bioassay development.
Handlingand Use:
FA-PEG-COOH is sensitive to light and temperature. Forbest use, material should always be kept in low temperature in dry condition.Protect from light.
Avoid frequent thaw and freezing. For moreinformation about using this product,
StorageConditions:
FA-PEG-COOH should bestored at -20℃.Desiccate. Protect from light. Materials may be handled under inert gas forbest stability.
References:
Methods------ Afolic acid-functionalized dual-emissive nanoprobe for “double-check”luminescence imaging of cancer cells.
RelatedProducts:
FA-PEG-NHS, FA-PEG-FITC
FA-PEG-Maleimide ,FA-PEG-SH
FA-PEG-NH2,DSPE-PEG-FA
Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.