Folic acid-PEG-Maleimide,FA-PEG-MAL
作者:Folic acid-PEG-Maleimide,FA-PEG-MAL 发布时间:2022-07-27 14:58:02
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商品型号:R-MFA-1K,2K,3.4K,5K,10K
英文简称:Maleimide (polyethylene glycol) folic acid
分子量:1K,2K,3.4K,5K,10K
规格:100mg,500mg
Folicacid-PEG-Maleimide,FA-PEG-MAL
Maleimide (polyethylene glycol) folic acid
Synonym: Folate PEGMaleimide, Maleimide PEG Folate, Maleimide PEG Folic acid
ProductStructure:
ProductSpecifications:
CatalogNumbers:PS2-MFA-1K,2K,3.4K,5K,10K.
Appearance: Orange/yellowto brownish solid.
Solubility:5mg/mL in hot water, DMSO.
Stability: 1 Years at-20°C, Desiccate.Protect from light.
CASNumber:-
MolecularWeight(PEG): 1K,2K,3.4K,5K,10K.
Reactivegroup: MAL.
Description:
FA-PEG-MAL is one of reactive folate PEG derivatives that have a folic acid on one terminusof PEG chain and a maleimide group on the other PEG end. Folic acid is alsoknown as vitamin M, vitamin B9 or pteroyl-L-glutamic acid. Folic acid is anessential bioactive molecule for numerous biological functions. It participatesin the synthesis, repairing and methylation of DNA as well as to act as acofactor in many biological reactions. Maleimide functionalized folic acid PEG allowsthe attachment of folic acid to other molecules and materials quickly andefficiently through reaction between thiol and maleimide. Maleimide reacts withsulfhydryl (thiol) groups at neutral pH with high specificity and efficiency.PEG chain between maleimide and folate offers with higher water solubility,flexible linker structure and enhanced stability. Molecules or materialsconjugated with PEG folic acid are useful for targeted drug delivery, cellularimaging and bioassay development.
Handlingand Use:
FA-PEG-MAL is sensitive to light and temperature. Forbest use, material should always be kept in low temperature in dry condition.Protect from light.
Avoid frequent thaw and freezing. For moreinformation about using this product,
StorageConditions:
FA-PEG-MAL should bestored at -20℃.Desiccate. Protect from light. Materials may be handled under inert gas forbest stability.
RelatedProducts:
FA-PEG-NHS, FA-PEG-FITC
FA-PEG-COOH ,FA-PEG-SH
FA-PEG-NH2,DSPE-PEG-FA
Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.