NHS-SS-PEG-Cholesterol: NHS dithio PEG Cholesterol is one of ' Cholesterol derivatives that can react with primary amine groups. Cholesterol is an essential lipid component to build and maintain basic animal cell functions. In addition to its structural functiona, cholesterol is also the important precursor for the biosynthesis of steroid hormones, bile acids and vitamin D. Succinimidyl ester (NHS) functionalized PEG cholesterol can react with primary amine groups derived from proteins, antibodies, peptdies and many other molecules with high efficiency. Reaction between NHS and amine allows conjugation of cholesterol moiety to those molecules quickly and easily. Resulted cholesterol conjugates can be used for biological system study, drug delivery and many other applications. Dithio linkage between NHS and PEG cholesterol can be easily cleaved by disulfide reducing reagents such as DTT or TCEP, thus conjugated PEG choesterol can be reversibly released. PEG linker between NHS and cholesterol offers better water solubility, reduced steric hindrance and enhanced stability. Physical Properties: Appearance: Off-white/white solid; Solubility: Soluble in water, DMSO and DMF; Reactive group: Succinimidyl ester (NHS); Functional moiety: Cholesterol; Reactive toward: Primary amine (-NH2); Storage Conditions: Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
瑞禧生物是您专业的小分子合成定制合作伙伴。我们专注于为医药研发、材料科学及学术研究提供从毫克到公斤级的一站式合成解决方案。无论是常规分子、复杂手性化合物、同位素标记物还是特定杂质，我们的资深团队都能凭借先进技术平台高效完成。我们始终坚持严格的质量控制，确保产品纯度与结构准确，并恪守保密承诺。选择瑞禧生物，就是选择可靠与精准，让我们以卓越的合成能力，加速您的创新突破。欢迎垂询，定制您的专属分子。