Name:ETC-1002
Synonyms:Bempedoic acid, ESP-55016
CAS Number:738606-46-7
Formula:C19H36O5
M.w.:344.49
DMSO (mg/mL)Max Solubility:68
DMSO (mM)Max Solubility:197.39
Form:free base
SMILES:CC(C)(CCCCCC(O)CCCCCC(C)(C)C(O)=O)C(O)=O
ALogP:5.18
Target:AMPK,ATP-citrate lyase,LDL
Pathway:PI3K/Akt/mTOR
Information:ETC-1002 (Bempedoic acid, ESP-55016),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
瑞禧生物是您专业的小分子合成定制合作伙伴。我们专注于为医药研发、材料科学及学术研究提供从毫克到公斤级的一站式合成解决方案。无论是常规分子、复杂手性化合物、同位素标记物还是特定杂质，我们的资深团队都能凭借先进技术平台高效完成。我们始终坚持严格的质量控制，确保产品纯度与结构准确，并恪守保密承诺。选择瑞禧生物，就是选择可靠与精准，让我们以卓越的合成能力，加速您的创新突破。欢迎垂询，定制您的专属分子。