Name:Duloxetine
Synonyms:LY-248686
CAS Number:116539-59-4
Formula:C18H19NOS
M.w.:297.41
DMSO (mg/mL)Max Solubility:The physical form of the compound is liquid, which can be dissolved in any proportion.
DMSO (mM)Max Solubility:N/A
Form:free base
SMILES:CNCCC(OC1=CC=CC2=CC=CC=C12)C3=CC=CS3
ALogP:3.846
Target:5-HT Receptor,Serotonin Transporter
Pathway:Neuronal Signaling
Information:Duloxetine (LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake.
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