Name:Nafamostat mesilate (FUT-175)
Synonyms:Futhan, FUT-175
CAS Number:82956-11-4
Formula:C19H17N5O2.2CH4O3S
M.w.:539.58
DMSO (mg/mL)Max Solubility:20
DMSO (mM)Max Solubility:37.07
Form:Dimesylate
SMILES:C[S](O)(=O)=O.C[S](O)(=O)=O.NC(=N)NC1=CC=C(C=C1)C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(N)=N
ALogP:1.364
Target:Apoptosis related,COVID-19,SARS-CoV,Serine Protease
Pathway:Proteases
Information:Nafamostat mesilate (Futhan, FUT-175) is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19. Nafamostat Mesilate attenuates inflammation and apoptosis.
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