生物活性：Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Buprofezin-d6 相关抗体:
Catalase Antibody (YA552)
Catalase Antibody (YA811)
C Reactive Protein Antibody (YA941)
PARK7/DJ1 Antibody (YA1799)
C Reactive Protein Antibody (YA939)
C Reactive Protein Antibody (YA940)
PON1 Antibody (YA1666)
PON2 Antibody (YA1688)
分子量：311.48
Formula：C16H17D6N3OS
CAS 号：2140803-94-5
非标记 CAS：69327-76-0
中文名称：扑虱灵-d6； 噻嗪酮-d6
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (538 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Ji X, et al. Potential hepatic toxicity of buprofezin at sublethal concentrations: ROS-mediated conversion of energy metabolism. J Hazard Mater. 2016 Dec 15;320:176-186.
 [Content Brief]
[2]. YoshioIzawa, et al. Inhibition of chitin biosynthesis by buprofezin analogs in relation to their activity controlling Nilaparvata lugens Stål. Pestic Biochem Physiol, 1985, 24(3): 343-347.
[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
 [Content Brief]