生物活性：Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant[1][2].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Rapamycin-d3 相关抗体:
Phospho-mTOR (Ser2448) Antibody (YA171)
mTOR Antibody (YA281)
RHEB Antibody
FKBP12 Antibody
FKBP51 Antibody
FKBP52 Antibody
Phospho-mTOR (Ser2448) Antibody (YA691)
Hamartin Antibody
4E BP1 Antibody
mTOR Antibody
Phospho-4E BP1 (Thr46) Antibody
Phospho-mTOR (Ser2481) Antibody
Raptor Antibody (YA1519)
FKBP38 Antibody (YA2803)
RICTOR Antibody
4E BP2 Antibody (YA1079)
4E BP3 Antibody (YA1080)
FKBP6 Antibody (YA2920)
Tuberin Antibody (YA3037)
分子量：917.19
Formula：C51H76D3NO13
CAS 号：392711-19-2
非标记 CAS：53123-88-9
性状：固体
颜色：White to off-white
中文名称：雷帕霉素 d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years
In solvent：-80°C：6 months，-20°C：1 month