生物活性：Venetoclax-d8 is deuterium labeled Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy[1][2][3].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Venetoclax-d8 相关抗体:
Bcl-2 Antibody
Bcl2 Antibody
Bax Antibody (YA591)
Bad Antibody
Bak Antibody (YA592)
BAX Antibody (YA825)
Bcl-XL Antibody
Bim Antibody
BNIP3 Antibody
PUMA Antibody
MCL1 Antibody
Bak Antibody
Bax Antibody (YA826)
Bcl2 Antibody (YA824)
BNIP3L Antibody
BAG2 Antibody (YA1398)
Phospho-PML Protein (Ser518) Antibody (YA2632)
Bid Antibody
BAG1 Antibody (YA932)
BAG1 Antibody (YA933)
Bcl10 Antibody (YA1188)
BAP31 Antibody (YA1320)
BCL2L1 Antibody (YA1359)
BAG3 Antibody (YA2240)
Bok Antibody (YA2289)
BPR Antibody (YA2393)
DYNLL1 Antibody (YA2724)
Bcl2 L14 Antibody (YA2740)
Bcl2 A1 Antibody (YA2743)
Phospho-Bad (Ser112) Antibody (YA3099)
分子量：876.49
Formula：C45H42D8ClN7O7S
CAS 号：1257051-06-1
非标记 CAS：1257044-40-8
性状：固体
颜色：White to yellow
中文名称：维奈妥拉-d8
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month