生物活性：Nintedanib-13C,d3 is the 13C- and deuterium labeled Nintedanib. Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[77].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Nintedanib-13C,d3 相关抗体:
FGFR2/CD332 Antibody
Phospho-PDGFR beta (Y740) Antibody
VEGF Receptor 2 Antibody (YA014)
FGFR1 Antibody
FGFR1 Oncogene Partner Antibody
FGFR2 Antibody
FGFR3 Antibody
PDGFR alpha Antibody
FGF2 Antibody
VEGF Receptor 1 Antibody
VEGFA Antibody
VEGF Receptor2 Antibody
FGF1 Antibody (YA1430)
PDGF B Antibody (YA1556)
FGFR4 Antibody (YA1588)
PLGF Antibody (YA1812)
PDGFR beta Antibody (YA1925)
VEGFD Antibody (YA2385)
FGF19 Antibody (YA2672)
TACC3 Antibody (YA2921)
Phospho-PDGFR beta (Tyr740) Antibody (YA3062)
FGF21 Antibody (YA3276)
PGF Antibody (YA1434)
Neuropilin 1 Antibody (YA1831)
VEGFB Antibody (YA2627)
分子量：543.64
Formula：C3013CH30D3N5O4
非标记 CAS：656247-17-5
性状：固体
颜色：White to off-white
中文名称：尼达尼布-13C,d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month