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Ranitidine-d6 hydrochloride,盐酸雷尼替丁 d6 (盐酸盐「同位素标记抑制剂」

作者:瑞禧生物 发布时间:2025-06-16 09:13:53 次浏览

生物活性:Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A)[1]. Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice[2][3].
IC50 & Target:H2 Receptor
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Ranitidine-d6 hydrochloride 相关抗体:
ADGRE1 (F4/80) Antibody (YA002)
ADGRE1 (F4/80) Antibody (YA920)
分子量:356.90
Formula:C13H17D6ClN4O3S
CAS 号:1185238-09-8
非标记 CAS:66357-59-3
性状:固体
颜色:Yellow to brown
中文名称:盐酸雷尼替丁 d6 (盐酸盐)
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)