生物活性:Promethazine-d4 (hydrochloride) is the deuterium labeled Promethazine hydrochloride. Promethazine hydrochloride is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
IC50 & Target:H1 Receptor
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Promethazine-d4 hydrochloride 相关抗体:
ADGRE1 (F4/80) Antibody (YA002)
ADGRE1 (F4/80) Antibody (YA920)
分子量:324.90
Formula:C17H17D4ClN2S
CAS 号:1173018-74-0
非标记 CAS:58-33-3
性状:固体
颜色:Off-white to yellow
中文名称:盐酸异丙嗪 d4 (盐酸盐)
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)