生物活性：Ranolazine-d8 (dihydrochloride) is the deuterium labeled Ranolazine dihydrochloride. Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine dihydrochloride is also a partial fatty acid oxidation inhibitor[3].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Ranolazine-d8 dihydrochloride 相关抗体:
Annexin VI Antibody
xCT Antibody (YA006)
Calbindin Antibody
Calreticulin Antibody
xCT Antibody (YA652)
Cardiac Troponin I/TNNC1 Antibody
Alpha-ENaC Antibody
SCGN Antibody (YA1167)
RAMP1 Antibody (YA1818)
Annexin V Antibody (YA1829)
Striatin 4 Antibody (YA2088)
Fibulin 5 Antibody (YA2448)
RASGRP1 Antibody (YA2546)
Fibulin 1 Antibody (YA2831)
EFEMP1 Antibody (YA2883)
CRCP Antibody (YA3350)
CRMP2 Antibody (YA3370)
Annexin VII Antibody (YA1138)
Parvalbumin Antibody (YA1249)
SLC12A1 Antibody (YA1403)
Annexin IV Antibody (YA1921)
SERCA2 ATPase Antibody (YA1931)
CRMP1 Antibody (YA1941)
Stromal Interaction Molecule 1 Antibody (YA2092)
SERCA1 ATPase Antibody (YA2157)
TrpV5 Antibody (YA2284)
NCX1 Antibody (YA2331)
Scramblase 1 Antibody (YA2419)
CRMP5 Antibody (YA2497)
CRMP3 Antibody (YA2563)
分子量：508.51
Formula：C24H27D8Cl2N3O4
CAS 号：1219802-60-4
非标记 CAS：95635-56-6
性状：固体
颜色：White to off-white
中文名称：盐酸雷诺嗪 d8 (双盐酸盐)
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)