生物活性：Cyclobenzaprine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Cyclobenzaprine (hydrochloride).
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[60].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Cyclobenzaprine-13C,d3 hydrochloride 相关抗体:
MTNR1A Antibody
分子量：315.86
Formula：C1913CH19D3ClN
CAS 号：1261394-10-8
非标记 CAS：6202-23-9
中文名称：阿米替林EP杂质B-13C,d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (527 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
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[2]. Kobayashi, H., Y. Hasegawa, and H. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35.
 [Content Brief]
[3]. Honda, M., T. Nishida, and H. Ono, Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. Eur J Pharmacol, 2003. 458(1-2): p. 91-9.
 [Content Brief]