生物活性:Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Dinotefuran-d3 相关抗体:
J-chain Antibody (YA1290)
PSCA Antibody (YA1479)
Butyrylcholinesterase Antibody (YA2460)
Nicotinic Acetylcholine Receptor alpha 4 Antibody (YA2616)
Nicotinic Acetylcholine Receptor alpha 5 Antibody (YA2659)
分子量:205.23
Formula:C7H11D3N4O3
CAS 号:2934813-27-9
非标记 CAS:165252-70-0
性状:固体
颜色:White to off-white
中文名称:呋虫胺-d3
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years
In solvent:-80°C:6 months,-20°C:1 month
纯度 & 产品资料
纯度: 95.82%
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[Content Brief]
[2]. Liu T, et al. Biochemical and genetic toxicity of dinotefuran on earthworms (Eisenia fetida). Chemosphere. 2017 Jun;176:156-164.
[Content Brief]