生物活性:Flucytosine-13C,15N2 (NSC 103805-13C,15N2; Ro 2-9915-13C,15N2) is a 13C- and 15N-labeled Flucytosine (HY-B0139).
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Flucytosine-13C,15N2 相关抗体:
SDHA Antibody
分子量:132.07
Formula:C313CH4FN15N2O
CAS 号:1216616-31-7
非标记 CAS:2022-85-7
性状:固体
颜色:White to off-white
中文名称:氟胞嘧啶-13C,15N2;5-氟胞嘧啶-13C,15N2
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
纯度 & 产品资料
纯度: 98.06%
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.
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[2]. Vermes A, et al. Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. J Antimicrob Chemother. 2000 Aug;46(2):171-9.
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[3]. Te Dorsthorst DT, et al. In vitro interaction of flucytosine combined with amphotericin B or fluconazole against thirty-five yeast isolates determined by both the fractional inhibitory concentration index and the response surface approach. Antimicrob Agents Chemother. 2002 Sep;46(9):2982-9.
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