生物活性：Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Valproic acid-d15 相关抗体:
BNSP Antibody
FACL4 Antibody
BrdU Antibody (YA578)
GAPDH Antibody
Glucose 6 Phosphate Dehydrogenase Antibody
HDAC1 Antibody
HDAC6 Antibody
METTL3 Antibody
HDAC4 Antibody (YA741)
TSG101 Antibody
SATB2 Antibody
Alkaline Phosphatase Antibody
Calnexin Antibody (YA573)
CD4 Antibody
HDAC10 Antibody
HDAC2 Antibody
HDAC3 Antibody
HDAC4 Antibody
Jagged1 Antibody
Lamin A/C Antibody
Lamin B1 Antibody
LAMP1 Antibody
LAMP2 Antibody (YA713)
LAMP2a Antibody
NQO1 Antibody (YA697)
NQO1 Antibody (YA261)
NUMB Antibody
OPA1 Antibody
RBM3 Antibody
Synaptophysin Antibody (YA043)
分子量：159.30
Formula：C8HD15O2
CAS 号：362049-65-8
非标记 CAS：99-66-1
性状：液体（密度：0.91 g/cm3）
颜色：Colorless to light yellow
中文名称：丙戊酸 d15
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Pure form
-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month