生物活性:Donepezil-d5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注[1]。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Donepezil-d5 相关抗体:
CHRNA9 Antibody
ChAT Antibody
分子量:384.52
Formula:C24H24D5NO3
CAS 号:1128086-25-8
非标记 CAS:120014-06-4
性状:固体
颜色:White to off-white
中文名称:多奈哌齐-d5
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)