生物活性:Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4].
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Olaparib-d4-1 相关抗体:
PARP1 Antibody
PARP2 Antibody
Cleaved PARP Antibody
Cleaved-PARP1 Antibody
PARP1 Antibody (YA245)
StAR Antibody
SSB Antibody (YA668)
GTF2H1 Antibody (YA1067)
BRAT1 Antibody (YA2294)
BRCC36 Antibody (YA2298)
Killin Antibody (YA3144)
分子量:438.49
Formula:C24H19D4FN4O3
CAS 号:2143107-55-3
非标记 CAS:763113-22-0
性状:固体
颜色:White to off-white
中文名称:奥拉帕尼 d4
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years,4°C:2 years
In solvent:-80°C:6 months,-20°C:1 month