生物活性：Pentamidine-d4 (dihydrochloride) is the deuterium labeled Pentamidine dihydrochloride. Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities[1][2][3][4].
IC50 & Target：Trypanosoma
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Pentamidine-d4 dihydrochloride 相关抗体:
PFKFB3 Antibody
SDHA Antibody
DUSP1 Antibody
DUSP3 Antibody
MRP2 Antibody
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
PU.1/SPI1 Antibody (YA1116)
Intestinal Alkaline Phosphatase Antibody (YA1559)
PFKL Antibody (YA1597)
SHP2 Antibody (YA1643)
PP1C alpha/beta Antibody (YA1700)
PTP1B Antibody (YA1776)
PLEKHA1 Antibody (YA2145)
PGAM1 Antibody (YA2156)
DUSP6 Antibody (YA2280)
PRAS40 Antibody (YA3179)
PPP4C Antibody (YA687)
Sulfadimidine Antibody (YA906)
Elongation factor 2 Antibody (YA963)
Phospho-PTP1B (Ser352) Antibody (YA1027)
Phospho-PTP1B (Ser378) Antibody (YA1028)
Placental Alkaline Phosphatase Antibody (YA1038)
Placental Alkaline Phosphatase Antibody (YA1039)
PP1C alpha Antibody (YA1040)
PP1C alpha Antibody (YA1041)
SHP1 Antibody (YA1044)
SHP1 Antibody (YA1045)
Anthrax Protective gen Antibody (YA1060)
PP1C gamma Antibody (YA1068)
分子量：417.37
Formula：C19H22D4Cl2N4O2
CAS 号：1276197-32-0
非标记 CAS：50357-45-4
性状：固体
颜色：White to off-white
中文名称：喷他脒二盐酸盐-d4；喷它咪二盐酸盐-d4；戊烷脒二盐酸盐-d4；戊脘脒二盐酸盐-d4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)