生物活性：Hydrochlorothiazid-d2 is the deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Hydrochlorothiazid-d2 相关抗体:
Smad3 Antibody
TGF beta 1 Antibody
Smad1 Antibody
Smad2 Antibody
Smad4 Antibody
Smad5 Antibody
Phospho-Smad3 (Ser423/Ser425) Antibody
ATP1A1 Antibody
CD105 Antibody (YA547)
Noggin Antibody (YA698)
Phospho-Smad1 (Ser463/Ser465) Antibody
Phospho-Smad2 (Ser250) Antibody
Phospho-Smad3 (Ser423/425) Antibody
Smad2/3 Antibody
Inhibin beta A Antibody (YA2780)
Phospho-Smad5 (Ser463/465) Antibody (YA2838)
LGI1 Antibody (YA2885)
Inhibin alpha Antibody (YA1232)
Inhibin beta B Antibody (YA1677)
Cardiac Troponin C Antibody (YA2125)
Phospho-NDRG1 (Ser330) Antibody (YA2618)
Cardiac Troponin T Antibody (YA2719)
SAP97 Antibody (YA2731)
Kir2.1 Antibody (YA2871)
SARA Antibody (YA3226)
分子量：299.75
Formula：C7H6D2ClN3O4S2
CAS 号：1219798-89-6
非标记 CAS：58-93-5
性状：固体
颜色：White to off-white
中文名称：氢氯噻嗪 d2
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month