生物活性：Sitagliptin-d4 (phosphate) is the deuterium labeled Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1][2].
IC50 & Target：DPP-4
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Sitagliptin-d4 phosphate 相关抗体:
DPP4/CD26 Antibody (YA1274)
分子量：509.33
Formula：C16H14D4F6N5O5P
CAS 号：1432063-88-1
非标记 CAS：654671-78-0
性状：固体
颜色：White to off-white
中文名称：磷酸西他列汀 d4 (磷酸盐)
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)