生物活性：Mirtazapine-d3 is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1].
IC50 & Target[1]：5-HT2 Receptor
5-HT3 Receptor
体内研究(In Vivo)
米氮平 (腹膜内注射；10-50 mg/Kg；14 天) 处理可使心率、呼吸率、焦虑水平正常化并消除在 MeCP2 缺失小鼠中观察到的跳跃行为，从而改善表型评分[2]。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model:
MeCP2 null mice[2]
Dosage:
10-50 mg/Kg
Administration:
Intraperitoneal injection; 10-50 mg/Kg; 14 days
Result:
Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI.
分子量：268.38
Formula：C17H16D3N3
CAS 号：1216678-68-0
非标记 CAS：85650-52-8
性状：固体
颜色：White to off-white
中文名称：米氮平杂质13 d4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month