生物活性：Methyl syringate-d6 is the deuterium labeled Methyl syringate. Methyl syringate is a selective TRPA1agonist. Methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway. Methyl syringate is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a chemical marker of Asphodel monofloral honey. Methyl syringate contributes to the antibacterial activity of honey. Methyl syringate inhibits aflatoxin production. Methyl syringate can contribute to weight suppression. Methyl syringate can be studies for cancer prevention (e.g. lung cancer), suppression of hypoxia-induced inflammatory response and tumorigenesis[1][2][3][4].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Methyl syringate-d6 相关抗体:
COX2 Antibody
COX IV Antibody
COX2/Cyclooxygenase 2 Antibody
PFKFB3 Antibody
DUSP1 Antibody
DUSP3 Antibody
COX IV Antibody (YA867)
MRP2 Antibody
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
PU.1/SPI1 Antibody (YA1116)
Intestinal Alkaline Phosphatase Antibody (YA1559)
PFKL Antibody (YA1597)
TRPM8 Antibody (YA1609)
SHP2 Antibody (YA1643)
PP1C alpha/beta Antibody (YA1700)
PTP1B Antibody (YA1776)
PLEKHA1 Antibody (YA2145)
PGAM1 Antibody (YA2156)
DUSP6 Antibody (YA2280)
TRPM7 Antibody (YA2391)
Cyclooxygenase 1 Antibody (YA2537)
Cyclooxygenase 2 Antibody (YA2541)
PRAS40 Antibody (YA3179)
PPP4C Antibody (YA687)
Sulfadimidine Antibody (YA906)
Elongation factor 2 Antibody (YA963)
Phospho-PTP1B (Ser352) Antibody (YA1027)
Phospho-PTP1B (Ser378) Antibody (YA1028)
Placental Alkaline Phosphatase Antibody (YA1038)
分子量：218.24
Formula：C10H6D6O5
CAS 号：1182838-09-0
非标记 CAS：884-35-5
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (548 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Kim MJ, et al. The TRPA1 agonist, methyl syringate suppresses food intake and gastric emptying. PLoS One. 2013 Aug 218(8):e71603.
 [Content Brief]
[2]. Rosado T, et al. Methyl syringate: an efficient phenolic mediator for bacterial and fungal laccases. Bioresour Technol. 2012 Nov124:371-8.
 [Content Brief]
[3]. Tuberoso CI, et al. Methyl syringate: a chemical marker of asphodel (Asphodelus microcarpus Salzm. et Viv.) monofloral honey. J Agric Food Chem. 2009 May 13;57(9):3895-900.
 [Content Brief]
[4]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]
[5]. Joonwoo Park, et al., Methyl syringate, a TRPA1 agonist represses hypoxia-induced cyclooxygenase-2 in lung cancer cells, Phytomedicine, Volume 23, Issue 3, 2016, Pages 324-329, ISSN 0944-7113.
[6]. Ahn D, et al., Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance. Life. 2023; 13(6):1372.