瑞禧生物货号:Ruixi-B656650
化学名称:(S)-1-Boc-3-hydroxypiperidine
同义名称:(3S)-3-Hydroxy-1-piperidinecarboxylic Acid 1,1-dimethylethyl Ester; (S)-3-Hydroxypiperidine-1-carboxylic Acid tert-Butyl Ester; (S)-N-Boc-3-hydroxypiperidine; (S)-tert-Butyl 3-Hydroxypiperidine-1-carboxylate; 1,1-Dimethylethyl (3S)-3-Hydroxy-1-piperidinecarboxylate; 1-Boc-(3S)-3-hydroxypiperidine; tert-Butyl (S)-3-Hydroxypiperidine-1-carboxylate; (S)-N-Boc-3-hydroxypiperidine;
CAS号:143900-44-1
分子式:C₁₀H₁₉NO₃
Appearance:White to Light Beige Low-Melting Solid
Melting Point:38-41°C
分子量:201.26
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Ethyl Acetate (Sligh
产品类别:Building Blocks; Chiral Molecules;
产品应用:(S)-1-Boc-3-hydroxypiperidine is an important chiral intermediate for the synthesis of ibrutinib, an anticancer drug targeting B-cell malignancies. Synthesis of pharmaceutical intermediates including ibrutinib, the API of the newly approved drug Imbruvica, for the treatment of lymphoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献:Chen, L., et al.: Tetrahedron Lett., 58, 1644 (2017); Ju, X., et al.: Org. Process Res. Dev., 18, 827 (2014)
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