瑞禧生物货号：Ruixi-B645735
化学名称：(S)-Boc-2-carbamoyl-2,3-dihydro-1H-pyrrole
同义名称：S)-tert-Butyl 2-carbamoyl-2,3-dihydro-1H-pyrrole-1-carboxylate; (2S)-2-(Aminocarbonyl)-2,3-dihydro-1H-Pyrrole-1-carboxylic Acid 1,1-Dimethylethyl Ester
CAS号：709031-38-9
分子式：C₁₀H₁₆N₂O₃
分子量：212.25
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：(S)-Boc-2-carbamoyl-2,3-dihydro-1H-pyrrole is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
参考文献：Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),
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