瑞禧生物货号:Ruixi-B642900
化学名称:Boc-D-4,4'-biphenylalanine
同义名称:(αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-[1,1'-biphenyl]-4-propanoic Acid; (R)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-[1,1'-biphenyl]-4-propanoic Acid; (R)-3-(Biphenyl-4-yl)-2-[(tert-butoxycarbonyl)amino]propionic Acid
CAS号:128779-47-5
分子式:C₂₀H₂₃NO₄
Appearance:White Solid
Melting Point:125-128ºC
分子量:341.4
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
产品类别:Standards; Chiral Molecules; Amino Acids; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:Boc-D-4,4'-biphenylalanine is used as a reagent in the synthesis of pyrrolopyrimidine inhibitors of Akt as antitumor agents. Boc-D-4,4'-biphenylalanine is also used in the preparation of (-)-Bestatin-based inhibitors.
参考文献:Blake, J.F., et al.: Bioorg. Med. Chem. Lett., 20, 5607 (2010); Velmourougane, G., et al.: J. Med. Chem., 54, 1655 (2011)
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