瑞禧生物货号：Ruixi-B621162
化学名称：1-Boc-4-(6-aminopyridin-3-yl)piperazine-d4
同义名称：4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic Acid tert-Butyl Ester-d4; 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic Acid tert-Butyl Ester-d4; tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate-d4; tert-Butyl 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylate-d4
CAS号：1808106-94-6
Alternate CAS #
unlabelled: 571188-59-5
分子式：C₁₄H₁₈D₄N₄O₂
Appearance:Brown Solid
分子量：282.37
Solubility:Dichloromethane, Ethyl Acetate, Methanol
产品类别：Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：1-Boc-4-(6-aminopyridin-3-yl)piperazine-d4 is an intermediate in synthesizing Palbociclib-d4 (P139901), an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
参考文献：Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)
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