瑞禧生物货号:Ruixi-B619270
化学名称:N-Boc-3-hydroxy-L-valine
同义名称:N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-threonine; N-[(1,1-Dimethylethoxy)carbonyl]-3-hydroxy-L-valine; (S)-2-(tert-Butoxycarbonylamino)-3-hydroxy-3-methylbutanoic Acid
CAS号:102507-13-1
分子式:C₁₀H₁₉NO₅
Appearance:White to Off-White Solid
Melting Point:115 - 117°C
分子量:233.26
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
产品类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:N-Boc-3-hydroxy-L-valine is used as a reagent in the synthesis of metabolites of PPI-2458, which is a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). N-Boc-3-hydroxy-L-valine is also used in the preparation of Boceprevir (B674500)
参考文献:Arico-Muendel, C.C., et al.: Drug Metab. Dispos., 41, 814 (2013); Venkatraman, S., et al.: J. Med. Chem., 49, 6074 (2006)
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