瑞禧生物货号：Ruixi-B596403
化学名称：BMS 753
同义名称：4-​[[(2,​3-​Dihydro-​1,​1,​3,​3-​tetramethyl-​2-​oxo-​1H-​inden-​5-​yl)​carbonyl]​amino]​benzoic Acid
CAS号：215307-86-1
分子式：C₂₁H₂₁NO₄
分子量：351.4
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：BMS 753 is as been reported to be a RARα-selective agonist. Used to develop a series of small molecule inhibitors which affect specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease. This would aspire to reduce the attrition problem in drug discovery.
参考文献：Habchi, J. et al.: Proc. Natl. Acad. Sci. USA., 114, E200 (2017); Gericke, J. et al.: PLoS One, 8, 82843 (2013);
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