瑞禧生物货号：Ruixi-B596070
化学名称：BMS 299897
同义名称：2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluorobenzenebutanoic Acid;
CAS号：290315-45-6
分子式：C₂₄H₂₁ClF₃NO₄S
分子量：511.94
产品类别：Research Tools;
产品应用：BMS 299897 is a known γ-secretase inhibitor that effectively reduces amyloid β-peptide (Aβ) in transgenic mice and guinea pigs (1,2,3). Studies have shown the possibility of using BMS 299897 in the treatments for Alzheimer’s patients.
参考文献：(1) Anderson, J.J., et al.: Biochem. Pharmacol., 69, 689 (2005)
(2) Zheng, M., et al.: Xenoiotica., 39, 544 (2009)
(3) Narlawar, R., et al.: Bioorg. Medn. Chem. Letters., 17, 176 (2007)
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