瑞禧生物货号:Ruixi-B595870
化学名称:BML-286
同义名称:2-[[3-[(2-phenylacetyl)amino]benzoyl]amino]benzoic Acid; 2-[[3-[(phenylacetyl)amino]benzoyl]amino]benzoic Acid;
CAS号:294891-81-9
分子式:C₂₂H₁₈N₂O₄
分子量:374.39
产品类别:Research Tools;
产品应用:A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways.
参考文献:Grandy, D. et al.: J. Biol. Chem., 284, 24 (2009);
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