瑞禧生物货号:Ruixi-B595370
化学名称:2-Bromo-3-fluoro-5-nitroaniline
同义名称:2-Bromo-3-fluoro-5-nitrobenzenamine
CAS号:1309832-49-2
分子式:C₆H₄BrFN₂O₂
分子量:235.01
产品类别:Building Blocks; Miscellaneous;
产品应用:2-Bromo-3-fluoro-5-nitroaniline (CAS# 1309832-49-2) is used in the preparation of pyrimidinediamine compounds as protein kinase C inhibitors for the treatment of a variety of diseases and disorders. It is also used in the preparation of small molecules that enhance functional O-mannosylation of alpha-dystroglycan (α-DG) of which hypoglycosylation is associated with muscular dystrophies and cancer progression.
参考文献:Holland, S., et al.: PCT Int. Appl. (2012), WO 2012012619 A1; Lv, F., et al.: Bioorg. Med. Chem. 23, 7661 (2015);
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