瑞禧生物货号：Ruixi-B419015
化学名称：1,3-Bis(2-chloroethyl)urea
同义名称：1,3-Bis(2-chloroethyl)urea; 1,3-Bis(2-chloroethyl)urea; NSC 36198; Carmustine Related Compound A
CAS号：2214-72-4
分子式：C₅H₁₀Cl₂N₂O
Appearance:White to Off-White Solid
Melting Point:121-124ºC
分子量：185.05
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic, Unstable in Solution
产品类别：Standards; Environmental Standards, Mutagens and Metabolites;
产品应用：1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine (C183875), an alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献：Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),
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