瑞禧生物货号：Ruixi-B415255
化学名称：1,3-Bis(carboxymethyl)-1H-imidazolium
同义名称：2-(1-(Carboxymethyl)-1H-imidazol-3-ium-3-yl)acetate;
CAS号：117255-11-5
分子式：C₇H₈N₂O₄
Appearance:White to Pale Beige Solid
Melting Point:>215ºC (dec.)
分子量：184.15
Storage:-20°C, Inert atmosphere
Solubility:Water (Heated)
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：1,3-Bis(carboxymethyl)-1H-imidazolium is an intermediate in synthesizing 1,3-Bis(2-hydroxy-2,2-diphosphonoethyl)-imidazolium Soidum Salt(Zoledronic Acid Impurity) (B443840), which is an impurity of Zolendronic Acid (trihydrate: Z623501), a biphosphonate that is used for the management of osteoporosis and the treatment of bone metastases from various types of cancers.
参考文献：Kohno, N., et al.: J. Clin. Oncol., 23, 3314 (2005); Reid, I., et al.: New Engl. J. Med., 346, 653 (2002); Rosen. L., et al.: Cancer J., 7, 377 (2000)
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