瑞禧生物货号:Ruixi-B414135
化学名称:N,N'-Bis[4-chloro-3-trifluoromethylphenyl]urea
同义名称:Flucofuron; CTF-urea; Flucofenuron; 1,3-Bis(4-chloro-3-(trifluoromethyl)phenyl)urea; 4,4'-Dichloro-3,3'-bis(trifluoromethyl)-carbanilide
CAS号:370-50-3
分子式:C₁₅H₈Cl₂F₆N₂O
Appearance:White to Off-White Solid
Melting Point:236-238°C
分子量:417.13
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
产品类别:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:N,N'-Bis[4-chloro-3-trifluoromethylphenyl]urea is a compound related to that of Sorafenib (S676850) which is a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis.
参考文献:Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),
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