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CAS:114694-12-1|(5Z,7E)-(1S,3R)-1,3-Bis[tert-butyl(dimethylsilyl)oxy]-22-hydroxy-23,24-dinor-9,10-secochola-5,7,10(19)-triene

作者:瑞禧生物 发布时间:2024-08-12 09:52:03 次浏览

瑞禧生物货号:Ruixi-B413020
化学名称:(5Z,7E)-(1S,3R)-1,3-Bis[tert-butyl(dimethylsilyl)oxy]-22-hydroxy-23,24-dinor-9,10-secochola-5,7,10(19)-triene
同义名称:(βS,​1R,​3aS,​4E,​7aR)​-4-​[(2Z)​-​2-​[(3S,​5R)​-​3,​5-​Bis[[(1,​1-​dimethylethyl)​dimethylsilyl]​oxy]​-​2-​methylenecyclohexyli​dene]​ethylidene]​octahydro-​β,​7a-​dimethyl-1H-​indene-​1-​ethanol;
CAS号:114694-12-1
分子式:C₃₄H₆₂O₃Si₂
Appearance:White Solid
分子量:575.03
Storage:-20°C, Inert atmosphere
Solubility:Dichloromethane
产品类别:Standards; Vitamin Derivatives;
产品应用:(5Z,7E)-(1S,3R)-1,3-Bis[tert-butyl(dimethylsilyl)oxy]-22-hydroxy-23,24-dinor-9,10-secochola-5,7,10(19)-triene is an intermediate in synthesizing ZK 159222 (Z485800), a vitamin D receptor antagonist. It is a derivative of Vitamin D3 (V676045).
参考文献:Mizwicki, M., et al.: J. Bio. Chem., 284, 36292 (2009); Ochiai, E., et al.: Mol. Endocrinol., 19, 1147 (2005)
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