瑞禧生物货号：Ruixi-B118020
化学名称：2-((1-Benzylpiperidin-4-yl)methyl)-2-hydroxy-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
同义名称：2,3-Dihydro-2-hydroxy-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one
CAS号：329010-67-5
Alternate CAS #
120014-06-4
分子式：C₂₄H₂₉NO₄
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:147 - 148°C
分子量：395.49
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
产品类别：Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：2-((1-Benzylpiperidin-4-yl)methyl)-2-hydroxy-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one is a piperidine derivative of research interest in senile dementia for its activity as an acetylcholinesterase(AChE) inhibitor. This compound is an analogue of donepezil, an approved medication used to treat Alzheimer's disease, because of its reversible inhibition activity on AChE.
参考文献：Iimura, Y., Kosasa, T., PCT Int. Appl. 39 pp. Patent (2001) CODEN:PIXXD2;
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