瑞禧生物货号：Ruixi-B103355
化学名称：6-Bromo-3-hydroxypyrazine-2-carboxamide
同义名称：Br-T-705; 6-Bromo-3,4-dihydro-3-oxo-2-pyrazinecarboxamide;
CAS号：259793-88-9
分子式：C₅H₄BrN₃O₂
Appearance:Yellow Solid
Melting Point:190 - 193°C
分子量：218.01
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
产品应用：6-Bromo-3-hydroxypyrazine-2-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.
参考文献：Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014)
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