瑞禧生物货号：Ruixi-A170000
化学名称：N-Acetyl-4-benzoquinone Imine
同义名称：4-(Acetylimino)-2,5-cyclohexadien-1-one; Acetimidoquinone; N-Acetyl-p-benzoquinonimine; NAPQI;
CAS号：50700-49-7
分子式：C₈H₇NO₂
Appearance:Pale Yellow to Very Dark Orange Solid
Melting Point:>58C (dec.)
分子量：149.15
Storage:- 86°C
Solubility:Chloroform (Slightly, Sonicated), DMSO (Slightly)
Stability
Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4).
参考文献：(1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006)
(2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)
(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)
(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Delta is committed to providing cost-effective products that facilitate drug delivery with our customers.