瑞禧生物货号：Ruixi-C694995
化学名称：(-)-Corey Lactone Diol
同义名称：(3aR,4S,5R,6aS)Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; [3aR-(3aα,4α,5β,6aα)]Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one;
CAS号：32233-40-2
分子式：C₈H₁₂O₄
Appearance:Light Beige to Beige Solid
Melting Point:118-120°C
分子量：172.18
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
产品类别：Building Blocks; Chiral Molecules;
产品应用：(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards b-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
参考文献：Gal, Z. et al.: J. Chemother., 12, 274 (2000); Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008);
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