瑞禧生物货号：Ruixi-C380165
化学名称：(3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
同义名称：THIQ
CAS号：312637-48-2
分子式：C₃₃H₄₁ClN₆O₂
分子量：589.17
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：Melanocortin 4 receptors play important roles in the regulation of energy homeostasis, eating behavior and sexual functions (1). (3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide is a potent and selective melanocortin 4 receptor agonist (2,3). It inhibits parasympathetic preganglionic neurons in the brainstem and regulates sympathetic and parasympathetic preganglionic neurons.
参考文献：(1) Link, R., et al.: Eur J Pharmacol. 799, 58 (2017)
(2) Sohn, J.W., et al.: Cell. 152, 612 (2013)
(3) Martin, et al.: Eur. J. Pharmacol., 71, 454, (2002)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Delta is committed to providing cost-effective products that facilitate drug delivery with our customers.