瑞禧生物货号：Ruixi-C380155
化学名称：3-[[2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetyl]oxy]-1,1-dimethylpyrrolidinium Bromide
同义名称：Glycopyrrolate Bromide Impurity I
CAS号：1404453-68-4
Alternate CAS #
Free base: 1404617-94-2
分子式：C₁₉H₂₇BrClNO₃
分子量：432.78
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：3-[[2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetyl]oxy]-1,1-dimethylpyrrolidinium Bromide, is a Glycopyrronium Bromide (G656980) impurity, which has a broad pharmacology and medical applications. Glycopyrronium blocks muscarinic receptors, thus inhibiting cholinergic transmission. It is also used to reduce excessive saliva (sialorrhea).It also decreases acid secretion in the stomach and so may be used for treating stomach ulcers, in combination with other medications. Also, It can be used in treating asthma and COPD.
参考文献：Haddad E.B., et al.: Br. J. Pharma., 127, 413 (1999); Bajaj, V., et al.: Br. J. Dermatol., 157, 118 (2007); Miler, RJ., et al.: Arch. Pediatr. Adolesc. Med., 154, 1214 (2000); Kaltiala, E., et al.: J. Pharm. Pharmacol., 26, 352 (1974), Kongsrud, F., et al.: Acta Anaesthesiol. Scand., 26, 620 (1982),
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